April 13, 2018

Real world home blood pressure variability in over 56,000 individuals with nearly 17 million measurements

  • Kim K.
  • Nikzad N.
  • Normand A.
  • Quer G.
  • Schmidt N.
  • Steinhubl S.
  • Topol E.
  • Vegreville M.
  • Wineinger N.

© American Journal of Hypertension, Ltd 2017. All rights reserved. BACKGROUND: Using the data from 56,365 individuals, from 185 countries, and a Nokia Health Wireless blood pressure (BP) monitor, we investigated real-world characteristics of BP variability (BPV). METHODS: All included individuals self-measured and uploaded their BP using Bluetooth at least 20 times over a period of > 1 month at a frequency and duration of their choosing. In total, 16,904,844 BP measurements were analyzed, with a median of 146 measurements per person (interquartile range [IQR] 73-321) over a median of 14 months (IQR 7-31). SD, coefficient of variation, maximum BP, and maximum minus minimum BP difference were all calculated as measures of BPV. RESULTS: BPV showed a distinct pattern, influenced by season of year, day of week, and time of day. BPV index was higher in females compared with males (P < 0.001) and increased with age (P < 0.001). Compared to the weekend, the weekday BPV index was significantly higher, and this finding was more prominent in females (P = 0.001). In multivariate analysis, BPV index were significantly associated with age, gender, geographic location, and mean BP values. CONCLUSION: Using the largest BP data set we are aware of, with the benefits and limitations of real-world measurement, we could show the pattern of BPV and provide reference values that may be helpful in understanding the nature of BPV as self-measurement at home becomes more common, and help guide individualized management.

View Original Article

Recent Publications

May 01, 2019

Digital networks at the nexus of productivity growth

  • Kamat S.
  • Prakash S.
  • Saniee I.
  • Weldon M.

This paper takes a fresh look at the debate over the relationship between digital technology and productivity. The argument of economic historian Robert J. Gordon is that digital technology will not lead to increases in productivity such as we saw in the last century, based on his analysis of the ...

January 01, 2019

Friendly, appealing or both? Characterising user experience in sponsored search landing pages

  • Bron M.
  • Chute M.
  • Evans H.
  • Lalmas M.
  • Redi M.
  • Silvestri F.

© 2017 International World Wide Web Conference Committee (IW3C2), published under Creative Commons CC BY 4.0 License. Many of today's websites have recognised the importance of mobile friendly pages to keep users engaged and to provide a satisfying user experience. However, next to the experience provided by the sites themselves, ...

January 01, 2019

Analyzing uber's ride-sharing economy

  • Aiello L.
  • Djuric N.
  • Grbovic M.
  • Kooti F.
  • Lerman K.
  • Radosavljevic V.

© 2017 International World Wide Web Conference Committee (IW3C2), published under Creative Commons CC BY 4.0 License. Uber is a popular ride-sharing application that matches people who need a ride (or riders) with drivers who are willing to provide it using their personal vehicles. Despite its growing popularity, there exist ...